Tag: neuromuscular disease

Pulmonary function

Respiratory Muscle Strength and Control of Ventilation: Discussion (8)

Transdiaphragmatic pressure swings (APdi) during quiet breathing in patients with myotonic dystrophy are nearly three times that of normal seated subjects and are probably related to greater impedance to diaphragmatic motion caused either by chest wall stiffness or increase of tone in intercostal and abdominal wall muscles. Patients with muscular…

Pulmonary function

Respiratory Muscle Strength and Control of Ventilation: Discussion (7)

Respiratory Muscle Strength and Control of Ventilation: Discussion (7)

The increased Po.i relative to Ve measurements in the group with neuromuscular disease demonstrates that these two measurements are not comparable under these circumstances. In a study of eight normal volunteers undergoing C02 rebreathing during progressive curarization, Holle and coworkers also found that despite increasing muscle weakness and decreasing Ve,…