Tag: Apoptosis

Cell

An Overview of Cell Renewal in the Testis: DISCUSSION

High cell proliferation in the gilthead seabream during spermatogenesis results in an increased GSI and larger gonad area, whereas fish growth ceases in favor of testis development. At the end of spermatogenesis, the tubules and the efferent duct possess wide lumina full of free spermatozoa. The shedding of spermatozoa leads…

Cell

An Overview of Cell Renewal in the Testis: RESULTS

Reproductive Cycle of Gilthead Seabream Males The reproductive cycle of the gilthead seabream, a protandrous hermaphrodite teleost, can be divided into four stages: spermatogenesis, an asynchronous process that lasts for several months (from September to February), spawning (March), postspawning (from April to May), and resting (from June to September). The…

Cell

An Overview of Cell Renewal in the Testis: MATERIAL AND METHODS

Fish Healthy specimens of sexually mature male gilthead seabream Sparus aurata (Sparidae, Perciform, Teleostei), with a body weight (BW) of 100 g, were obtained in November 2002, from Predomar, S.L. (Carboneras, Spain). The fish were kept at the Spanish Oceanographic Institute (Ma-zarron, Murcia), in 14 m3 running-seawater aquaria (dissolved oxygen…

Cell

An Overview of Cell Renewal in the Testis: INTRODUCTION

Spermatogenesis, the formation of sperm, is a complex process in which spermatogonia divide and differentiate into spermatozoa. In fish, spermatogenesis appears to proceed in a similar fashion to that observed in other vertebrates, although with some important differences. In mammals, the germinal epithelium is constant throughout the year or it…

Colorectal polyposis

Colorectal polyposis and immune-based therapies: CONCLUSION

In one study, Xiang et al used a recombinant humanized antibody-IL-2 fusion protein to direct IL-2 to the tumour microenvironment and elicit a T cell-mediated eradication of established pulmonary and hepatic metastatic lesions of the colon in syngeneic mice . The T cells that were isolated from tumour-bearing mice following…