In our study, we assessed the effect of maturation on cardiac and respiratory responses to TAS in well-controlled conditions. Premature and full-term infants spend most of their time in “active” REM sleep, and we paid great attention to defining the state of alertness of infants during the entire testing procedure….
Respiratory Response to TAS Data obtained in each infant are summarized in Table 1. Control Ttot was significantly related to PCA (p<0.0001) (Table 2). The TAS provoked a prolongation of Ttot in 27 out of the 33 infants. The longest Ttot during TAS amounted 4.4 seconds (subject 8). In the…
All variables were measured during undisturbed “active” REM sleep; however, no dissociation between “phasic” and “tonic” REM sleep was attempted (see Fig 1, which illustrates a typical tracing). Any record where a sleep state change occurred or where persistence of the REM sleep state was questioned during TAS was eliminated…
Analyses Analysis of Cardiac Variables. The R-R intervals were measured on the ECG tracing, and the following R-R interval measurements were performed: “control R-R interval,” calculated as the mean R-R interval recorded during the 60-second period of undisturbed “active” (REM) sleep preceding TAS; cardiac variables measured during TAS: changes in…
Methods Trigeminal Airstream Stimulation Monitoring Techniques. The TAS was performed using a standardized technique and timing. The infants were in unmedicated sleep, in the supine position, and had been fed at least two hours earlier. Airstream stimulation was delivered through two parallel short plastic tubes to the inside of both…
The diving reflex in marine animals and man is associated with immediate apnea and bradycardia. Stimulation of the area innervated by the afferent trigeminal nerve may, in some newborns and infants, elicit reflex bradycardia and apnea which resemble those of a diving reflex. buy flovent inhaler A previous report has…