Category: Thrombolytic Therapy

Thrombolytic Therapy

Safety and Efficacy of Thrombolytic Therapy: Discussion (7)

Safety and Efficacy of Thrombolytic Therapy: Discussion (7)

It is important to remember that patients with SVC syndrome are at increased risk for recurrent DVT and pulmonary embolism and, therefore, should receive anticoagulation after either successful or unsuccessful thrombolytic therapy. Likewise, with symptom resolution and catheter preservation after thrombolytic therapy, anticoagulation should be maintained as long as the…

Thrombolytic Therapy

Safety and Efficacy of Thrombolytic Therapy: Discussion (5)

Safety and Efficacy of Thrombolytic Therapy: Discussion (5)

Cost was not a deciding factor in the use of a particular agent since the overall cost has been demonstrated to be equivalent when complications and hospital stay are taken into consideration. Urokinase was chosen because of superior results in the treatment of DVT, pulmonary embolism, and peripheral arterial occlusion…

Thrombolytic Therapy

Safety and Efficacy of Thrombolytic Therapy: Discussion (2)

Eleven patients in this series had central venous catheters that were considered to be contributing factors in the development of SVC syndrome. This subpopulation was more likely to have thrombosis as a cause of SVC syndrome, whereas obstruction, fibrosis, or compression was the major cause of SVC syndrome in the…

Thrombolytic Therapy

Safety and Efficacy of Thrombolytic Therapy: Discussion (1)

Safety and Efficacy of Thrombolytic Therapy: Discussion (1)

Traditionally, SVC syndrome has been considered a medical emergency. Lolach and Goodman found that 97 percent of their patients with SVC syndrome had underlying cancer as a cause and recommended that radiation therapy be instituted early without subjecting the patient to unnecessary diagnostic tests. They also suggested that anticoagulants and…