Category: Assisted reproductive technology

Assisted reproductive technology

Genetic risks associated with advanced assisted reproductive technology: CONGENITAL ANOMALIES IN IVF AND ICSI (Part 2)

While the finding of no increase in the rate of congenital malformation with assisted reproductive technology is reassuring, many researchers criticized the methodology, particularly the inadequacy of sample size and the lack of appropriate controls for valid comparison. One recent study designed to address the major methodological problems of previous…

Assisted reproductive technology

Genetic risks associated with advanced assisted reproductive technology: CONGENITAL ANOMALIES IN IVF AND ICSI (Part 1)

Studies designed to determine whether anomaly rates are increased in IVF and ICSI pregnancies are subject to similar pitfalls from confounding variables mentioned previously. More extensive neonatal examination following IVF and ICSI pregnancies compared with natural ones may be implemented. For instance, minor anomalies recorded in surveys of IVF and…

Assisted reproductive technology

Genetic risks associated with advanced assisted reproductive technology: TRANSMISSION OF EXISTING GENETIC ABNORMALITIES THROUGH ASSISTED REPRODUCTION (Part 1)

Obviously, existing genetic conditions of the parents can be transmitted to the offspring through assisted reproduction, as they would with natural conception, if feasible. Three genetic conditions of special relevance to male-factor infertility are microdeletion of the Y-chromosome, congenital bilateral absence of the vas deferens (CBAVD) and Klinefelter’s syndrome. The…